The SARS-CoV-2 isolate, originating from a clinical respiratory specimen collected in India, is preserved at
ICMR-NIV, Pune. It is characterized through genome sequencing and real-time RT-PCR targeting a conserved viral
gene, ensuring accurate identification. As part of the national repository, this isolate can support research
on diagnostics, therapeutic evaluation, vaccine-related studies, and preparedness initiatives.
The Nipah virus isolate, obtained from human oropharyngeal samples during an outbreak in Kerala, is preserved
at ICMR-NIV. Characterization includes complete genome sequencing and RT-PCR using Nipah-specific targets. This
isolate can aid studies on pathogen evolution, diagnostic strengthening, antiviral research, and outbreak
preparedness, given Nipah's high public-health relevance.
The Crimean-Congo Hemorrhagic Fever virus isolate, sourced from a clinical serum sample collected in Gujarat,
is maintained at ICMR-NIV. Molecular confirmation through RT-PCR and full-genome sequencing supports accurate
characterization. This isolate can enable research on disease mechanisms, antiviral assessment, diagnostic
refinement, and preparedness efforts for regions experiencing recurring CCHF activity.
The Chandipura virus isolate, obtained from clinical material collected in India, is preserved at ICMR-NIV. It
has been characterized through genome sequencing and molecular assays targeting a conserved viral gene. As part
of the national viral collection, it supports studies on neurotropic viral infections, diagnostic development,
vector-borne disease surveillance, and preparedness programs.
The measles virus isolate, collected from a throat swab in Gujarat, is maintained in the national reference
collection at ICMR-NIV. Characterization includes genome-based typing and standard molecular assays focused on
key viral genes. This isolate can support measles elimination efforts through molecular surveillance, vaccine
monitoring, and understanding lineage circulation.
The mumps virus isolate, obtained from an oral swab in Maharashtra, is preserved at ICMR-NIV. It is
characterized through genetic analysis and RT-PCR targeting a routinely assessed viral region. This isolate can
serve as a valuable tool for mumps surveillance efforts, supporting outbreak investigation, lineage mapping,
vaccine-effectiveness assessments, and diagnostic improvements.
The rubella virus isolate, collected in the early years of national surveillance from a suspected case in
Maharashtra, is maintained at ICMR-NIV. As a historic genotype reference with a detailed sequencing record, it
is vital for understanding rubella evolution, supporting congenital rubella syndrome tracking, evaluating
vaccine performance, and strengthening national elimination initiatives.
The Zika virus isolate, sourced from Aedes mosquitoes in Maharashtra, is preserved at ICMR-NIV. It is
characterized using RT-PCR targeting a conserved envelope-gene region. This isolate supports vector-borne
disease surveillance, research on Zika transmission and pathogenesis, and development of improved diagnostics,
aiding preparedness in regions with emerging Zika activity.
The Influenza A H3N2 isolate from Puducherry is preserved at ICMR-NIV and confirmed through genome sequencing
and real-time PCR. As part of national influenza monitoring, the isolate may be helpful in antigenic analysis,
antiviral-resistance tracking, and seasonal vaccine-strain recommendations.
The Influenza A H1N1 isolate collected in Bangalore is maintained at ICMR-NIV. Characterization includes
full-genome sequencing and real-time PCR confirmation. This isolate supports genomic surveillance, resistance
profiling, and refinement of national vaccine-strain selection strategies for seasonal influenza.
The Influenza B Victoria-lineage isolate obtained in Pune is preserved at ICMR-NIV. Characterization includes
full-genome sequencing and real-time PCR confirmation. The isolate can contribute to national influenza
surveillance by supporting strain monitoring, antigenic evaluation, and vaccine-formulation development.
